Van de Ven Double Ends The Toffees' Unbeaten Streak at Brand New Stadium
The Dutch defender became the initial backline player to score two goals in a Premier League match for Spurs since Jan Vertonghen in spring 2013.
At a glance
The Spurs defender heads home two times in opening period
Everton's defender has equalizer disallowed after video check
Pape Matar Sarr scores final goal in dying moments
The defeat is the Merseyside club's initial at their new ground
Micky van de Ven found the net on two occasions as Tottenham extended their unbeaten run in away games in the Premier League and handed the Toffees their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having left their historic home behind after more than a century at the conclusion of last season.
But Spurs captain the Dutchman pounced twice from set-pieces in the opening 45 minutes to place their strong form at jeopardy, and they were unable to turn it around before Pape Matar Sarr - set up by former Toffees attacker the Brazilian - nodded in a third to seal the victory.
Jake O'Brien believed he had levelled the scores a short while after Van de Ven's opener, directing a powerful header past Guglielmo Vicario from an set-piece.
Beto, in the meantime, missed a number of opportunities, while Vicario made a series of fine stops to guarantee the London club went five away games unbeaten in the English top flight.
But the VAR intervened, advising Craig Pawson to review the score on the pitchside monitor and the referee ruled that Jack Grealish and Iliman Ndiaye were in an illegal position and had impeded with the Tottenham goalkeeper.
This victory moves the manager's side into third place in the Premier League, a handful of points off north London rivals and leaders Arsenal.
The Merseyside club remain 14th and are six points ahead of the relegation zone.
Spurs breakdown: Van de Ven fulfils role at both ends of pitch
Following a uninspiring midweek performance in the Champions League against Monaco, where they managed a only attempts on target, Frank opted for the French striker in attack instead of former Toffees player the Brazilian.
The summer signing was failed to make much of an impact before being substituted for Richarlison after 60 minutes on the pitch, but it emerged he proved unnecessary in the end.
Centre-back Van de Ven converted into an attacking force to be feared.
Spurs' first goal came from a well-worked set-piece play, with Rodrigo Bentancur heading the ball toward the six-yard box for an free the defender to score.
And the captain - filling in as skipper in the Argentine's absence - added his next goal in first-half stoppage time as he outjumped Jordan Pickford to head home.
The Dutchman was equally outstanding in defensive duties, partnering effectively with his defensive colleague as the pair handled superbly with the 34 crosses sent their way by the opposition.
Everton analysis: Everton missing striker's instinct
Everton's new home had been a happy hunting ground, but it seems the freshness may have faded slightly and supporters flocked to the gates after Sarr's final goal for Spurs.
The break in the team's winning streak at home will not be a major worry for David Moyes, but their attacking woes are.
The forward and Thierno Barry - the Everton's pair of established strikers - had scored just one league goal combined before Sunday's match.
And they were failed to contribute to that poor record on a damp and dreary evening on in Liverpool.
Beto's form was epitomized when he opted to overhead kick a golden opportunity from close range, even with having room and time to reposition for a more conventional shot that would have tested Vicario.
The substitute, too, failed to influence the game after replacing Beto in the 65th minute.
It was not for a lack of opportunity. The majority of the home side's offensive moves came through the winger and Ndiaye, who tirelessly whipped dangerous balls into the Spurs penalty area.
Upcoming fixtures for these two sides?
Everton: The team travel to Sunderland in the top flight on Monday, 3 November at 8 PM.
Spurs: The London club travel to Newcastle's ground on Wednesday, 29 October for their fourth-round Carabao Cup match against Newcastle.